This abstract (Epub ahead of print) was published July 16th 2014 in Medicine and Science in Sports and Exercise. STUDY: Aspects of Respiratory Muscle Fatigue in a Mountain Ultramarathon Race. Wüthrich TU, Marty J, Kerherve H, Millet GY, Verges S, Spengler CM. Abstract: “Ultra-marathon running offers the unique possibility to investigate the mechanisms contributing to the limitation of endurance performance. Investigations of locomotor muscle fatigue show that central fatigue is a major contributor to the loss of strength in lower limbs after an ultra-marathon. Also respiratory muscle fatigue is known to limit exercise performance but only limited data are available on changes in respiratory muscle function after ultra-marathon running and it is not known whether the observed impairment is caused by peripheral and/or central fatigue.” Conclusions: “Ultra-endurance running reduces respiratory muscle strength, for inspiratory muscles shown to result from significant peripheral muscle fatigue with only little contribution of central fatigue. This contrasts findings in locomotor muscles. Whether this difference between muscle groups results from inherent neuromuscular differences, their specific pattern of loading or other reasons remains to be clarified.” View the full article. View list of published research that used POWERbreathe as the IMT intervention of choice in POWERbreathe in Research. Find more published research on our Inspiratory Muscle Training Research blog.