Influence of Gender and Inspiratory Muscle Training on the Perception of Dyspnea in Patients With Asthma

“Men and women respond differently to asthma. Maximal inspiratory mouth pressure (PImax), ?2-agonist consumption, and perception of dyspnea (POD) were measured in 22 women and 22 men with mild persistent-to- moderate asthma. Next, the women were randomized into two groups: those who received inspiratory muscle training and those who received sham training. The training ended when the PImax of the training group was equal to that of the male subjects. POD was then measured once again.”

Conclusion:

“Our study shows that the inspiratory muscles in women could be trained within 20 weeks to reach the same strength as in their male counterparts. This increase in inspiratory muscle strength completely concealed the gender differences in POD and ?2 -agonist consumption, suggesting that the gender differential in maximal inspiratory muscle strength is responsible for the fact that women are more symptomatic than men. However, other possibilities for the gender differences could not be negated in our study, and further investigations are needed to completely clarify the issue.”

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